KLF4 Antilichaam - C-terminalgebied: Biotine (ARP38430_P050-Biotin)

Kruppel-like factor 4 (gut)

EZF, GKLF

9314

O43474

NP_004226

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the C terminal region of human KLF4

The mammalian Kruppel-like transcription factor, KLF4 is involved in preventing centrosome amplification following DNA damage caused by gamma-irradiation. It is both necessary and sufficient in preventing centrosome amplification following gamma-radiation-induced DNA damage and does so by transcriptionally suppressing cyclin E expression n. Kruppel-like factor 4 is also known to exhibit checkpoint function during the G1/S and G2/M transitions of the cell cycle.

EP300; CREBBP; SETD7; CTBP1; Dlg4; APP; CUL2; VHL; UBC; TCEB2; SP1; RELA; PRKCD; PPARG; SMARCA4; HDAC2; HDAC7; KAT5; HDAC1; HDAC5; ELK1; KLF6; TP53

Biotin

Polyclonal Antibody

IHC, WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

50kDa

Natesampillai, S., Am. J. Physiol. Endocrinol. Metab. 294 (2), E385-E391 (2008)

Wet Ice

470

KLF4

KLF4

Rabbit

Krueppel-like factor 4

NM_004235

AGCGKTYTKSSHLKAHLRTHTGEKPYHCDWDGCGWKFARSDELTRHYRKH