KLHDC8B Polyklonale Antilichaam, APC Vervoeging

Involved in pinching off the separated nuclei at the cleavage furrow and in cytokinesis (PubMed:20107318) . Required for mitotic integrity and maintenance of chromosomal stability. Protects cells against mitotic errors, centrosomal amplification, micronucleus formation and aneuploidy. Plays a key role of midbody function involving abscission of the daughter cells during cytokinesis and appropriate chromosomal and nuclear segregation into the daughter cells (PubMed:22988245, PubMed:23713010) .

FLJ11302; FP17659; Kelch domain containing 8B; Kelch domain containing protein 8B; Kelch domain-containing protein 8B; KLD8B_HUMAN; Klhdc8b; MGC35097; MGC94736.

200942

Q8IXV7

Cytoplasm

Human

201-300/354

KLHDC8B

APC

KLH conjugated synthetic peptide derived from human KLHDC8B

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

650nm/660nm

1µg/µl

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

200942

Mouse, Rat, Dog, Cow, Sheep, Rabbit