KNG1 Antilichaam

This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK) . HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.

3827

P01042

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 148-427 of human KNG1 (NP_000884.1) .

Unconjugated

Primary Antibodies

Apoptosis, Cell Cycle, Signal Transduction

Affinity purification

HepG2

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 45-48kDa

IgG

WB: 1:500 - 1:2000

KNG1

U-87MG

Mouse liver

Mouse kidney

Mouse heart

Kininogen 1

Homo sapiens

KNG1, BDK, KNG, BK

WB

Liquid