KNG1 Antilichaam - C-terminalgebied: Biotine (ARP45681 P050-Biotine)

Kininogen 1

BK, BDK, KNG, HMWK

3827

P01042-2

NP_000884.1

Human

The immunogen is a synthetic peptide directed towards the C-terminal region of human KNG1

This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK) . HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Human: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

32kDa

Wet Ice

291

KNG1

KNG1

Rabbit

Kininogen-1

NM_000893.3

ISLMKRPPGFSPFRSSRIGEIKEETTSHLRSCEYKGRPPKAGAEPASERE