[KO Gevalideerd] HDAC1 Konijn pAb (APR17360N)

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality [KO Validated] HDAC1 Rabbit pAb (APR17360N) .

GON-10; HD1; RPD3; RPD3L1; HDAC1

3065

Q13547

Nucleus

IF (Human acute leukemia cells) WB (Human acute leukemia cells, HL60, Hut102, 293T, Homo sapiens, Mus musculus, Rattus norvegicus, Sus scrofa) IP (Human acute leukemia cells, Rattus norvegicus) ChIP (Rattus norvegicus)

WB 1:500 - 1:2000 IHC 1:100 - 1:200 IF 1:50 - 1:100 IP 1:50 - 1:100

Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Calculated MW: 55kDa Observed MW: 62kDa

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3065

https://www.uniprot.org/uniprot/Q13547

SGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKLA