Koolstofanhydrase IX (CA9) Mouse Monoclonal Antibody [Kloon ID: LBI1G7]

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-basebalance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.

Carrier-free (BSA/glycerol-free) CA9 mouse monoclonal antibody, clone LBI1G7

CAIX; MN

Homo sapiens carbonic anhydrase 9 (CA9), mRNA.

768

Q16790

Unconjugated

Nitrogen metabolism

Nitrogen metabolism

WB 1:2000, IHC 1:50, Flow 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Transmembrane

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

CA9

https://www.ncbi.nlm.nih.gov/gene/?term=768

https://www.uniprot.org/uniprot/Q16790