KRAS-antilichaam, KO gevalideerd

This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.

3845

P01116

Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 30-188 of human KRAS (NP_004976.2) .

Unconjugated

Primary Antibodies

Antibody is Knockout validated.

Apoptosis, Cancer, Cell Cycle, Immunology, Signal Transduction

Affinity purification

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

IgG

WB: 1:500 - 1:2000

KRAS

Kirsten rat sarcoma viral oncogene homolog

Homo sapiens

KRAS, C-K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS3, RASK2, NS, CFC2

WB

Liquid