KRT1 Antilichaam - middengebied: Biotine (ARP42278 P050-Biotine)

Keratin 1

K1, CK1, EHK, EHK1, EPPK, KRT1A, NEPPK

3848

P04264

NP_006112

Human, Rat, Dog, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human KRT1

KRT1 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma.The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

MDM2; LGR4; EED; ESR1; ADRB2; PAN2; Iqcb1; Nphp4; Cep290; Nphp1; Invs; GRDX; VCAM1; UBC; ITGA4; FN1; CDH1; APOA1; ALB; MAGOH; EIF4A3; KRT10; KRT9; KRT2; SLC25A5; SHC1; PIK3R2; INPPL1; GRB2; EPS15; CRK; AP2M1; CBL; UBASH3B; NEDD8; CAND1; DCUN1D1; COPS5; CO

Biotin

Polyclonal Antibody

IHC, WB

Affinity Purified

0.5 mg/ml

Dog: 86%; Human: 100%; Rabbit: 93%; Rat: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

66kDa

Schweizer, J., (2006) J. Cell Biol. 174 (2), 169-174

Wet Ice

644

KRT1

KRT1

Rabbit

Keratin, type II cytoskeletal 1

NM_006121

GSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKS