KRT18 Antilichaam - C-terminal regio : HRP (ARP40206 T100-HRP)

Keratin 18

K18, CK-18, CYK18

3875

P05783

NP_000215

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the C terminal region of human KRT18

KRT18 (Keratin 18) is type I intermediate filament chain. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis.KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.

KRT18; GOLGA2; UBC; HAUS1; CCDC146; MDM2; EED; HNRNPU; FLII; FKBP3; DDX1; C14orf166; RTCB; CNOT1; SEC16A; RPL14; RFC2; UPF2; BBS7; PAN2; BBS4; BBS2; BBS1; SMARCD1; ORC5; NOS2; KRT8; KPNA2; ITGA4; HRAS; GRN; FN1; EP300; ATF2; CDH1; CDC5L; YTHDC1; PIAS4; TX

HRP: Horseradish Peroxidase

Polyclonal Antibody

IHC, WB

KRT18 is supported by BioGPS gene expression data to be expressed in HepG2

0.5 mg/ml

Cow: 93%; Dog: 86%; Guinea Pig: 100%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 77%; Rat: 100%; Zebrafish: 83%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

47kDa

Ku, N.O., (2005) Gastroenterology 129 (3), 885-893

Wet Ice

430

KRT18

KRT18

Rabbit

Keratin, type I cytoskeletal 18

NM_000224

ALLNIKVKLEAEIATYRRLLEDGEDFNLGDALDSSNSMQTIQKTTTRRIV