KRT2A Antilichaam - middengebied: Biotine (ARP41735_P050-Biotin)

Keratin 2

K2e, KRTE, CK-2e, KRT2A, KRT2E

3849

P35908

NP_000414

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human KRT2A

KRT2A is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma.The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

KRT40; KRT38; KRT31; KRT19; KRT13; Fbxl16; LGR4; EED; ADRB2; PAN2; Nphp4; IQCB1; VCAM1; UBC; FN1; EIF4A3; MAGOH; KRT10; KRT1; UBASH3B; SHC1; PIK3R2; INPPL1; GRB2; EPS15; CRK; AP2M1; CBL; CAND1; DCUN1D1; COPS5; COPS6; CUL1; CUL2; CUL3; CUL4A; CUL4B; CUL5

Biotin

Polyclonal Antibody

IHC, WB

Affinity Purified

0.5 mg/ml

Cow: 79%; Dog: 100%; Guinea Pig: 79%; Horse: 88%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 79%; Rat: 81%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

70kDa

Bloor, B.K., (2003) Am. J. Pathol. 162 (3), 963-975

Wet Ice

639

KRT2

KRT2

Rabbit

Keratin, type II cytoskeletal 2 epidermal

NM_000423

EVKAQYEEIAQRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELN