KRT8 Antilichaam, KO gevalideerd

This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.

3856

P05787

Human, Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 1-483 of human KRT8 (NP_002264.1) .

Unconjugated

Primary Antibodies

Antibody is Knockout validated.

Cancer, Cell Cycle, Signal Transduction

Affinity purification

293T

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 53kDa

IgG

KRT8

NIH/3T3

Keratin 8

Homo sapiens

KRT8, CARD2, CK8, CYK8, K2C8, K8, KO, CK-8

WB, IHC, IF

Liquid