KSHVK8a Antilichaam [8C12G10G1]

Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma- (2) -herpesvirus subfamily and has been closely linked to the Kaposi’s sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman’s disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. KSHV K8 and K8.1 open reading frames are juxtaposed and span from nucleotide (nt) 74850 to 76695 of the virus genome. A K8 pre-mRNA overlaps the entire K8.1 coding region, and alternative splicing of KSHV K8 and K8.1 pre-mRNAs each produces three isoforms (α , β , and γ ) of the mRNAs.

4961462

Q2HR82

Q2HR82

Virus

Ni-NTA purified recombinant human KSHV K8α expressed in E. Coli strain BL21 (DE3) .

8C12G10G1

Unconjugated

Primary Antibodies

Infectious Disease

Batch dependent

Ascitic fluid containing 0.03% sodium azide.

None

Blue Ice

KSHV K8α monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG2a

K8

BZIP transcription factor

Human herpesvirus 8

James J et al. Proc. Natl. Acad. Sci Vol. 1996. 93, pp. 14862-14867.

E3 SUMO-protein ligase K-bZIP

WB, ICC

123831254