KSL- W

KSL-W is a multifunctional antibacterial peptide with immune regulatory function. KSL-W has a chemotactic effect on neutrophils. KSL-W can induce neutrophil F-actin polymerization dependent on the Gαi protein signaling pathway. KSL-W can inhibit the production of reactive oxygen species (ROS) in neutrophils. KSL-W can be used for research on infection control and inflammation regulation[1].

1206554-01-9

12352209

Bacterial; Reactive Oxygen Species (ROS)

Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Infection; Inflammation/Immunology

O=C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC2=CNC3=CC=CC=C23)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CCCCN)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCCN)N

C68H106N16O10

1307.67

[1]Williams RL, et al. Antimicrobial decapeptide KSL-W enhances neutrophil chemotaxis and function. Peptides. 2012 Jan;33 (1) :1-8.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P11140/

Peptides

No Development Reported