KU70 Antilichaam

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V (D) J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

2547

P12956

Human, Mouse, Rat, Monkey

A synthetic peptide corresponding to a sequence within amino acids 500-600 of human KU70 (NP_001460.1) .

Unconjugated

Primary Antibodies

Cancer, Cell Cycle

Affinity purification

SKOV3

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 70kDa

IgG

XRCC6

COS7

SW480

HeLa

Mouse brain

Mouse liver

X-ray repair complementing defective repair in Chinese hamster cells 6

Homo sapiens

G22P1, ML8, KU70, TLAA, CTC75, CTCBF, G22P1

WB, IHC, IF

Liquid