Kv beta 2 Polyklonale Antilichaam, PE Vervoeging

Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles, and other excitable cells. The KV gene family encodes more than 30 genes that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution, and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming a-subunits (KV), which include the KV1, KV2, KV3, and KV4 proteins, and accessory or KV-subunits that modify the gating properties of the coexpressed KV subunits. Differences exist in the patterns of trafficking, biosynthetic processing, and surface expression of the major KV1 subunits (KV1.1, KV1.2, and KV1.4) expressed in rat and human brain, suggesting that the individual protein subunits are highly regulated to control for the assembly and formation of functional neuronal channels. KV beta.2 can also be designated KCNAB2, KKv beta2.1 or AKR6A5.

AKR6A5; HKv beta 2; HKvbeta 2; HKvbeta2.1; HKvbeta2.2; K+ channel subunit beta 2; K+ channel beta 2 subunit; KCNA2B; KCNAB 2; KCNAB2; KCNK2; Kv Beta 2; Kvbeta2; MGC117289; Potassium channel shaker chain beta 2; Potassium voltage gated channel shaker related subfamily; Potassium voltage gated channel shaker related subfamily beta member 2; Voltage gated potassium channel beta 2 subunit; Voltage gated potassium channel subunit beta 2

Cytoplasm

Rat

251-350/367

Kv beta 2

PE

KLH conjugated synthetic peptide derived from human KCNA2B/Kv beta 2

IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

496,564nm/578nm

1µg/µl

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Human, Mouse, Dog, Cow, Sheep, Pig, Rabbit, Zebrafish