Kv2.1 (KCNB1) (NM 004975) Humaan Recombinant Proteïne

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog (s) . This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members. [provided by RefSeq, Jul 2008]

Purified recombinant protein of Human potassium voltage-gated channel, Shab-related subfamily, member 1 (KCNB1), Gln509-Cys813, with N-terminal His tag, expressed in E. coli, 50ug

DEE26; DRK1; Kv2.1

3745

Q14721

NM_004975

20q13.13

E. coli

N-His

Taste transduction

Taste transduction

>50 ug/mL as determined by microplate BCA method

> 80% as determined by SDS-PAGE and Coomassie blue staining

Liquid

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.

Druggable Genome, Ion Channels: Potassium, Transmembrane

32.7 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

KCNB1

Human

NP_004966

https://www.ncbi.nlm.nih.gov/gene/3745

https://www.uniprot.org/uniprot/Q14721

https://www.ncbi.nlm.nih.gov/nuccore/NM_004975

https://www.ncbi.nlm.nih.gov/nuccore/NP_004966