KYNU Antilichaam - C-terminaal gebied: Biotine (ARP46037 P050-Biotine)

Kynureninase

KYNUU, VCRL2

8942

Q16719

NP_003928

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast

The immunogen is a synthetic peptide directed towards the C terminal region of human KYNU

Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway.Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Two transcript variants encoding different isoforms have been found for this gene.Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Two transcript variants encoding different isoforms have been found for this gene.

LDHAL6B; BCCIP; CNDP2; NAGK; CHORDC1; C11orf58; NDRG1; GDA; SMS; RPS6KA1; PEPD; MVD; LDHA; GSR; GNS; CSE1L; ADSS; LYN; UBC; PALM2; SMEK2; SSU72; SIRT1; NUP210; SEC23IP; COIL; TPM3; SMARCD2; SGTA; PPM1G; ASNS

Biotin

Polyclonal Antibody

IHC, WB

Affinity Purified

KYNU is supported by BioGPS gene expression data to be expressed in HepG2

0.5 mg/ml

Cow: 86%; Dog: 86%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 86%; Rat: 86%; Yeast: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

52kDa

Suzuki, Y., Gene 200 (1-2), 149-156 (1997)

Wet Ice

465

KYNU

KYNU

Rabbit

Kynureninase

NM_003937

LAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP