L-Cycloserine (standaard)

L-Cycloserine (Standard) is the analytical standard of L-Cycloserine. This product is intended for research and analytical applications. L-Cycloserine ((S) -4-Amino-3-isoxazolidone) is an oral inhibitor of the enzyme gamma-aminobutyric acid (GABA) transaminase (GABA-t) and branched-chain transaminases in Mycobacterium tuberculosis. L-Cycloserine has anticonvulsant properties and inhibits the synthesis of neurotensin in mouse brains[1][2][3][4].

339-72-0

(S) -Cycloserine (Standard) ; (S) -4-Amino-3-isoxazolidone (Standard)

12352005

GABA Receptor; HIV; Reference Standards

Anti-infection; Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Neurological Disease; Cancer

O=C1NOC[C@@H]1N

C3H6N2O2

102.09

[1]Tathyana Mar Amorim Franco, et al. Mechanism-Based Inhibition of the Mycobacterium tuberculosis Branched-Chain Aminotransferase by d- and l-Cycloserine. ACS Chem Biol. 2017 May 19;12 (5) :1235-1244.|[2]S H Chung, et al. L-cycloserine: a potent anticonvulsant. Epilepsia. 1984 Jun;25 (3) :353-62.|[3]P Polc, et al. L-cycloserine: behavioural and biochemical effects after single and repeated administration to mice, rats and cats. Neuropharmacology. 1986 Apr;25 (4) :411-8.|[4]K S Sundaram, et al. Inhibition of cerebroside synthesis in the brains of mice treated with L-cycloserine. J Lipid Res. 1985 Apr;26 (4) :473-7.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-B1122R/

Reference Standards