L-Fucose

L-Fucose (6-Deoxy-L-galactopyranose) is an orally active dietary sugar. L-Fucose is one of the key metabolites involved in the interaction between humans and the intestinal microbiota. L-Fucose binds to proteins as a post-translational modification through the fucosylation process, thereby regulating the behavior and function of proteins. L-Fucose has shown the ability to inhibit tumor growth and increase the infiltration of immune cells within tumors. L-Fucose can be used in cancer and anti-tumor immune research[1].

87-96-7

6-Deoxy-L-galactopyranose

12352005

H302-H315-H319-H335

Endogenous Metabolite

Metabolic Enzyme/Protease

COVID-19-immunoregulation

Cancer; Inflammation/Immunology

O[C@H]1[C@@H](O)[C@H](O)C(O)O[C@H]1C

C6H12O5

164.16

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

[1]Adhikari E, et al. L-fucose, a sugary regulator of antitumor immunity and immunotherapies. Mol Carcinog. 2022 May;61 (5) :439-453.|[2]Kim J, et al. L-Fucose is involved in human-gut microbiome interactions. Appl Microbiol Biotechnol. 2023 Jun;107 (12) :3869-3875.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W854443/

Reference compound1

No Development Reported