Lactogeen, placenta

Bovine recombinant placental lactogen, one polypeptide chain containing 164 amino and an additional Ala at N-terminus acids and having a molecular mass of ~ 23 kDa, was purified by proprietary chromatographic techniques . Bovine recombinant placental lactogen is also capable of activating human and other heterologous growth hormone receptors but not ruminant GH receptors.

Chorionic somatomammotropin hormone 1, BPLP-I, Placental lactogen I

281097

P09611

AAA30739.1

M33268.1

Bovine

Bovine

AEDYAPYCKNQPGNCRIPLQSLFERATLVASNNYRLAREMFNEFNKQFGEGKNFTSKVINSCHTEFMTTPNNKEAAANTEDEALLRLVISLLHSWDEPLHQAVTELLHRNGASPDILARAKEIEDKTKVLLEGVEMIQKRVHPGEKKNEPYPVWSEKSSLTADDEDVRQTAFYRMFHCLHRDSSKISTYINLLKCRFTPC

It is recommended to reconstitute the lyophilized bovine recombinant placental lactogen in sterile water or 0.4% NaHCO3 adjusted tp pH 8-9, not less than 100µg/ml, which can then be further diluted to other aqueous solutions, preferably in presence of carrier protein.

< 0.1 ng/µg of protein (< 1EU/µg)

> 98.0% as determined by Gel filtration and SDS-PAGE gel.

Recombinant bovine recombinant placental lactogen is fully biologically active as evidenced by inducing proliferation of Nb2 cells.

199

Lyophilized

Water

23.0 kDa

E. coli

AEDYAP