LAIR1 Antilichaam

The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants.

3903

Q6GTX8

Human, Mouse, Rat

Recombinant protein of human LAIR1

Unconjugated

Primary Antibodies

Immunology

Affinity purification

B cells

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 35kDa

IgG

WB: 1:1000 - 1:4000

LAIR1

Jurkat

HL-60

Raji

Mouse brain

Mouse liver

Leukocyte-associated immunoglobulin-like receptor 1

Homo sapiens

LAIR1, leukocyte-associated immunoglobulin-like receptor 1, leukocyte-associated Ig-like receptor 1, LAIR-1, CD305

WB

Liquid