LANA-IN-1

LANA-IN-1 (compound 8) is an N-acetyl-derived LANA inhibitor with antiviral activity against herpesvirus. In fluorescence assays using the LANA probe LBS2, 1 mM LANA-IN-1 shows an inhibition rate of 32%. LANA-IN-1 may inhibit the interaction between LANA and the viral genome[1].

2221-00-3

4- (1H-Imidazol-1-yl) aniline

12352005

H315, H319, H335

HSV

Anti-infection

Infection

99.89

NC(C=C1)=CC=C1N2C=CN=C2

C9H9N3

159.19

H315, H319, H335

[1]Kirsch P, et al. Fragment-Based Discovery of a Qualified Hit Targeting the Latency-Associated Nuclear Antigen of the Oncogenic Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8. J Med Chem. 2019 Apr 25;62 (8) :3924-3939.

Room Temperature

4°C (Powder, protect from light)

http://file.medchemexpress.com/batch_PDF/HY-W015462/LANA-IN-1-SDS-MedChemExpress.pdf

Reference compound1

No Development Reported