LANCL2 Antilichaam

LANCL2 (LanC-like protein 2), also known as TASP (testis-specific adriamycin sensitivity protein) or GPR69B, is a 450 amino acid member of the LanC-like protein family (1) . It is expressed highly in brain and testis and localized to the nucleus, cytoplasm and cell membrane (2,3) . LANCL2 is necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes (3,4) .

55915

Q9NS86

NP_061167

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Signal Transduction

LANCL2 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1303 - Human Brain Tissue Lysate

1 mg/mL

LANCL2 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

LANCL2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

LANCL2 antibody is human, mouse and rat reactive.

LANCL2

LanC lantibiotic synthetase component C-like 2 (bacterial)

Homo sapiens

Mayer H, Pongratz M, and Prohaska R. Molecular cloning, characterization, and tissue-specific expression of human LANCL2, a novel member of the LanC-like protein family. DNA Seq. 2001; 12:161-6.

Sturla L, Fresia C, Guida L, et al. Binding of abscisic acid to human LANCL2. Biochem. Biophys. Res. Commun. 2011; 415:390-5.

Landlinger C, Salzer U, and Prohaska R. Myristoylation of human LanC-like protein 2 (LANCL2) is essential for the interaction with the plasma membrane and the increase in cellular sensitivity to adriamycin. Biochim. Biophys. Acta. 2006; 1758:1759-67.

Zeng M, van der Donk WA, Chen J. Lanthionine synthetase C-like protein 2 (LanCL2) is a novel regulator of Akt. Mol. Biol. Cell 2014; 25:3954-61.

LanC lantibiotic synthetase component C-like 2, GPR69B, LanC-like protein 2, TASP, Testis-specific adriamycin sensitivity protein

ELISA, WB, IHC-P

8923911

Liquid