Lansoprazol N-oxide

Lansoprazole N-oxide (Comound 2) is the overoxidized by-product found in the synthesis of the proton pump inhibitor Lansoprazole. Lansoprazole N-oxide is promising for research of duodenal and gastric ulcers, reflux oesophagitis, and Zollinger–Ellison syndrome[1].

213476-12-1

12352005

H302-H315-H319-H335

Drug Metabolite

Metabolic Enzyme/Protease

Metabolism-protein/nucleotide metabolism

Metabolic Disease; Inflammation/Immunology

O=S(C1=NC2=CC=CC=C2N1)CC3=C(C)C(OCC(F)(F)F)=CC=[N+]3[O-]

C16H14F3N3O3S

385.36

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

[1]Reddy G M, et al. Synthesis and characterization of metabolites and potential impurities of lansoprazole, an antiulcerative drug[J]. Synthetic Communications®, 2008, 38 (20) : 3477-3489.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-Z7660/

Reference compound1

No Development Reported