Lapeptide

La peptide (LAP) is an internal ribosome entry site (IRES) inhibitor. La peptide efficiently enters cells, blocks binding of cellular transacting factors to viral IRES, followed by inhibiting IRES-mediated translation. La peptide can be used for RNA viruses research, such as hepatitis C (HCV) and poliovirus (PV) [1].

12352209

Enterovirus; HCV

Anti-infection

COVID-19-anti-virus

Infection

O=C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CS)C(N[C@@H](CC1=CNC=N1)C(N[C@@H](CCC(N)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](CC3=CC=C(C=C3)O)C(N[C@@H](CC4=CC=CC=C4)C(NCC(N[C@@H](CC(O)=O)C(N[C@@H](CC5=CC=CC=C5)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)N

C99H141N23O27S

2117.38

[1]Dasgupta A, et al. Targeting internal ribosome entry site (IRES) -mediated translation to block hepatitis C and other RNA viruses. FEMS Microbiol Lett. 2004 May 15;234 (2) :189-99.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P10974/

Peptides

No Development Reported