LAPTM4B Antilichaam - middengebied: HRP (ARP47442_P050-HRP)

Lysosomal protein transmembrane 4 beta

LC27, LAPTM4beta

55353

Q86VI4-3

NP_060877

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human LAPTM4B

LAPTM4B is a multi-pass membrane protein. It belongs to the LAPTM4/LAPTM5 transporter family. LAPTM4b has active role in disease progression of malignant cells and is involved in cell proliferation and multidrug resistance. The genetic polymorphism of LAPTM4B is a potential risk factor for the development of colon cancer and gastric cancer. The research results also indicated that LAPTM4B may be a clinically useful prognostic indicator for ovarian carcinoma and may play a role in human hepatocellular carcinoma.

NAALADL2; TFRC; NEDD4; UBC

HRP: Horseradish Peroxidase

Polyclonal Antibody

IHC, WB

Affinity Purified

There is BioGPS gene expression data showing that LAPTM4B is expressed in HEK293T

0.5 mg/ml

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

35kDa

Cheng, X.J., (2008) Ann. Oncol. 19 (3), 527-532

Wet Ice

317

LAPTM4B

LAPTM4B

Rabbit

Lysosomal-associated transmembrane protein 4B

NM_018407

YPNSIQEYIRQLPPNFPYRDDVMSVNPTCLVLIILLFISIILTFKGYLIS