Larotrectinib
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Larotrectinib is a potent (IC50’s < 11 nM) inhibitor of tropomyosin receptor kinases A, B, and C (TrkA, B, and C) .1 It is >100 fold selective against a panel of 229 kinases. Larotrectinib markedly attenuated bone cancer pain and significantly blocked the formation of neuroma-like structures and the sprouting of sensory nerve fibers. Larotrectinib caused substantial tumor regression in various cancers displaying TRK gene fusions.2-4 Larotrectinib is the first tissue agnostic drug approved by the FDA.
Unconjugated
Yellow solid
RT
Beschrijving
Larotrectinib Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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