Lawson (Standaard)

Lawsone is an orally active naphthoquinone dye that can be isolated from the leaves of Lawsonia inermis. Lawsone can induce apoptosis. Lawsone has antibacterial, antitumor and antioxidant activities. Lawsone can be used in anti-tumor drug research[1][2][3][4][5].

83-72-7

12352005

Apoptosis; Fungal

Anti-infection; Apoptosis

Infection; Cancer

O=C1C(O)=CC(C2=C1C=CC=C2)=O

C10H6O3

174.16

[1]Tripathi RD, et al. A fungitoxic principle from the leaves of lawsonia inermis lam. Experientia. 1978 Jan 15;34 (1) :51-2.|[2]Munday R, et al. Haemolytic activity and nephrotoxicity of 2-hydroxy-1,4-naphthoquinone in rats. J Appl Toxicol. 1991 Apr;11 (2) :85-90.|[3]Sauriasari R, et al. Cytotoxicity of lawsone and cytoprotective activity of antioxidants in catalase mutant Escherichia coli. Toxicology. 2007 Jun 3;235 (1-2) :103-11.|[4] Wang SB, et al. Lawsone suppresses azoxymethane mediated colon cancer in rats and reduces proliferation of DLD-1 cells via NF-κB pathway. Biomed Pharmacother. 2017 May;89:152-161.|[5]Li P, et al. Lawsone inhibits cell growth and improves the efficacy of cisplatin in SKOV-3 ovarian cancer cell lines. African Journal of Traditional, Complementary and Alternative Medicines, 2017, 14 (5) : 8-17.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N2493R/

Reference Standards