LC-2
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
2502156-03-6
PROTAC KRASG12C Degrader-LC-2
C12369-5mg
Ras
Apoptosis
C59H71ClFN11O7S
LC-2 is a first PROTAC capable of degrading endogenous KRASG12C with DC50s between 0.25 μM and 0.76 μM. LC-2 covalently binds KRASG12C with a MRTX849 warhead and recruits the E3 ligase VHL, inducing rapid and sustained KRASG12C degradation leading to suppression of MAPK signaling.
3 years -20°C powder
Beschrijving
LC-2 Beschikbaar in 1 mg. Bestel eenvoudig online met snelle levering.
Specificaties
Recent bekeken producten
Human Sertoli Cell Complete Medium
MBS2576755-01
100 mL
Urobilinogen protein
MBS5303823-01
100 mg
AffiniPure Goat Anti-Rabbit IgG H&L, HRP conjugated
GTR17765564-01
100 µL
Pribolab® Automatic Immunoaffinity Column Purification System
HWEQ-IM 5050
1 Unit
OneTaq Hot Start 2X Master Mix with GC Buffer
NEB M0485L
500 Reactions
HyperLadder 1kb
BIO-33053
100 Lanes
MicroMolar UDP assay kit - 100 assays
MUD100K
100 Assays
MEM Amino Acids Solution (50x) w/o: L-Glutamine
P08-30100
100 mL
Recent gezochte producten
Recombinant Human CD73 (T376A, M379T, C-Fc)
CW65-1mg
1 mg
Recombinant Human CD73 (T376A, M379T, C-Fc)
CW65-50ug
50 µg
Rabbit Monoclonal TdT Antibody (RM379)
NBP2-77436
100 µL
Mouse Monoclonal MCM7 Antibody (SPM379)
NBP2-53219-20ug
20 µg
Mouse Monoclonal MCM7 Antibody (SPM379)
NBP2-53219-100ug
100 µg
PEnter-NT5E (T376A/M379T) -Flag-His
PPL00480-2a
1 Each
MCM7 Antibody [SPM379]
33-735
100 µg
pEnter-NT5E(T376A/M379T)-Flag-His Plasmid
PVTB00480-2a
2 µg