LDN-193189
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1062368-24-4
DM3189
C08723-2mg
TGF-beta/Smad
TGF-beta/Smad
C1CN (CCN1) C2=CC=C (C=C2) C3=CN4C (=C (C=N4) C5=CC=NC6=CC=CC=C56) N=C3
C25H22N6
LDN-193189 (DM3189) is a selective BMP signaling inhibitor, inhibits the ALK1, ALK2, ALK3 and ALK6 with IC50s of 0.8 nM, 0.8 nM, 5.3 nM and 16.7 nM in the kinase assay, respectively. LDN-193189 inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50s of 5 nM and 30 nM in C2C12 cells, respectively, exhibits 200-fold selectivity for BMP versus TGF-β. For cell testing, the water-soluble S7507 LDN-193189 2HCl is recommended.This product has poor solubility, animal experiments are available, cell experiments please choose carefully!
2 years -80 in solvent
Beschrijving
LDN-193189 Beschikbaar in 2 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
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