LDOC1 Antilichaam - N-terminalgebied: HRP (ARP38983_P050-HRP)

Leucine zipper, down-regulated in cancer 1

Mar7, RTL7, BCUR1, Mart7, SIRH7

23641

O95751

NP_036449

Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human LDOC1

LDOC1 contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB) . The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB) . The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.

LENG1; TTC23; MEAF6; SH2D4A; CTNNBL1; DPPA4; FAM90A1; C1orf109; FAM208B; TBC1D7; PRPF31; LDOC1; PEG10; NXF1; ZBTB24; HDAC4; ATP6V1G1; HGS; LATS1; RAB29; TNNT1; TMSB4XP1; SDCBP; DPF2; PSMA1; MFAP1; BARD1; ATF4; AES; ZNF774; ZNF564; HAUS1; ZGPAT; CCDC33; IN

HRP: Horseradish Peroxidase

Polyclonal Antibody

IHC, WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Rabbit: 100%; Rat: 79%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

17kDa

Ross, M.T., (2005) Nature 434 (7031), 325-337

Wet Ice

146

LDOC1

LDOC1

Rabbit

Protein LDOC1

NM_012317

MVDELVLLLHALLMRHRALSIENSQLMEQLRLLVCERASLLRQVRPPSCP