LEFTY2 Antilichaam

This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. Alternate splicing of this gene results in multiple transcript variants.

7044

O00292

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 57-366 of human LEFTY2 (NP_003231.2) .

Unconjugated

Primary Antibodies

Cancer, Cell Cycle, Chemokines & Cytokines, Growth Factors, Immunology, Signal Transduction, Stem Cell

Affinity purification

LO2

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 41kDa

IgG

WB: 1:500 - 1:2000

LEFTY2

Mouse heart

Rat liver

Left-right determination factor 2

Homo sapiens

LEFTY2, EBAF, LEFTA, LEFTYA, MGC46222, TGFB4

WB

Liquid