LEFTY2 Antilichaam - N-terminaal gebied: Biotine (ARP42107_P050-Biotine)

Left-right determination factor 2

EBAF, LEFTA, TGFB4, LEFTYA

7044

O00292

NP_003231

Human, Mouse, Rat, Cow, Horse, Pig

The immunogen is a synthetic peptide directed towards the N terminal region of human LEFTY2

LEFTY2 is a member of the TGF-beta family of proteins. The protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in its gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of its gene in the endometrium.This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene.

ACSS3

Biotin

Polyclonal Antibody

IHC, WB

Affinity Purified

LEFTY2 is supported by BioGPS gene expression data to be expressed in RPMI 8226

0.5 mg/ml

Cow: 79%; Horse: 93%; Human: 100%; Mouse: 79%; Pig: 86%; Rat: 83%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

40kDa

Cornet, P.B., (2005) J. Clin. Endocrinol. Metab. 90 (2), 1001-1011

Wet Ice

366

LEFTY2

LEFTY2

Rabbit

Left-right determination factor 2

NM_003240

MWPLWLCWALWVLPLAGPGAALTEEQLLGSLLRQLQLSEVPVLDRADMEK