Lenalidomide
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Thalidomide analog which, like thalidomide,1 binds to cereblon which is the substrate recognition component of a cullin-dependent ubiquitin ligase and inhibits its autoubiquitination activity2. Induces degradation of T-cell repressors Ikaros (IKZF1) and Aiolos (IKZF3) leading to T cell activation2. Selective inhibition of IKZF1 and IKZF3 in multiple myeloma cells results in cell death3,4. Cell permeable. Caution: Teratogenic
Unconjugated
White solid
RT
Beschrijving
Lenalidomide Beschikbaar in 100 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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