LEPR-eiwit (C-human IgG1-Fc & His, Human)

LEPR

CD295, DB, LEP-R, LEPRD, OB-R, OBR

C-human IgG1-Fc & His

< 1.0 EU per μg of the protein as determined by the LAL method

≥ 90 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

Measured by its binding ability in a functional ELISA . Immobilized human Leptin at 1.25 μg/ml (100 μl/well) can bind human Leptin receptor with a linear range of 0.032-4.0 μg/ml .

Met1-Asp839

The recombinant human LEPR/Fc is a disulfide-linked homodimeric protein.The reduced monomer consists of 1065 amino acids and has a predicted molecular mass of 121.4 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh LEPR/Fc monomer is approximately 155-165 kDa due to glycosylation.

Human