Lercanidipine-d3

Lercanidipine-d3 is the deuterium labeled Lercanidipine. Lercanidipine is a third-generation, lipophilic, brain-penetrant, vascular-selective and orally active dihydropyridine-calcium channel blocker with a pIC50 of 7.74 (converts from μM). Lercanidipine has long lasting antihypertensive action as well as reno- and neuro-protective effect. Lercanidipine also shows anti-oxidant, anti-inflammatory and anti-apoptotic properties. Lercanidipine can be used in cardiovascular and neurological research[1][2][3][4][5].

1190043-34-5

12352005

Reactive Oxygen Species (ROS)

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Neurological Disease

O=C(C1=C(NC(C)=C(C1C2=CC=CC([N+]([O-])=O)=C2)C(OC)=O)C)OC(C)(CN(CCC(C3=CC=CC=C3)C4=CC=CC=C4)C([2H])([2H])[2H])C

C36H38D3N3O6

614.75

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W707863/

Isotope-Labeled Compounds

No Development Reported