Leukotrieen A-4 hydrolase Antilichaam / LTA4H

The protein encoded by this gene is an enzyme that contains both hydrolase and aminopeptidase activities. The hydrolase activity is used in the final step of the biosynthesis of leukotriene B4, a proinflammatory mediator. The aminopeptidase activity has been shown to degrade proline-glycine-proline (PGP), a neutrophil chemoattractant and biomarker for chronic obstructive pulmonary disease (COPD) . Several transcript variants encoding different isoforms have been found for this gene.

Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Flow cytometry: 1-3ug/million cells, Immunofluorescence: 5 µg/mL, ELISA: 0.1-0.5 µg/mL

P09960

Human, Mouse, Rat

An E.coli-derived human recombinant protein (amino acids Q137-D611) was used as the immunogen for the Leukotriene A-4 hydrolase antibody.

WB, IHC-P, FACS, IF, ELISA

Antigen affinity purified

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This Leukotriene A-4 hydrolase antibody is available for research use only.

After reconstitution, the Leukotriene A-4 hydrolase antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the Leukotriene A-4 hydrolase antibody should be determined by the researcher.

Cytoplasm, Nucleus

Immunofluorescent staining of FFPE human intestinal cancer tissue with Leukotriene A-4 hydrolase antibody (red) and DAPI nuclear stain (blue) . HIER: steam section in pH8 EDTA buffer for 20 min.