Levofloxacine (mesilaat)

Levofloxacin mesylate is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria. Levofloxacin mesylate inhibits the DNA gyrase and topoisomerase IV. Levofloxacin mesylate can be used for chronic periodontitis, airway inflammation and BK Viremia research. Levofloxacin mesylate shows anti-orthopoxvirus activity[1][2][3][4][5].

226578-51-4

12352005

H302-H315-H319-H335

Antibiotic; Bacterial; Topoisomerase

Anti-infection; Cell Cycle/DNA Damage

COVID-19-anti-virus

Cancer; Infection

C[C@H]1COC2=C3C(=CC(=C2N4CCN(C)CC4)F)C(=O)C(=CN13)C(=O)O.CS(=O)(=O)O

C19H24FN3O7S

457.47

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

[1]Drlica K, et al. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61 (3) :377-92.|[2]Smee DF, et al. A review of compounds exhibiting anti-orthopoxvirus activity in animal models. Antiviral Res. 2003 Jan;57 (1-2) :41-52.|[3]Rand A, et al. Effect of levofloxacin on some body tissues in mice. Effect of levofloxacin on some body tissues in mice. Iraqi Journal of Veterinary Sciences, 2021.|[4]JI B, et al. In vitro and in vivo activities of levofloxacin against Mycobacterium tuberculosis. Antimicrob Agents Chemother. 1995 Jun;39 (6) :1341-4.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W338859/

Reference compound1

Phase 4