Lifastuzumabvedotine
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Lifastuzumab vedotin (RG-7599; DNIB0600A) is an antibody-drug conjugate (ADC) that comprises a humanized IgG1 anti-NaPi2b monoclonal antibody (MNIB2126A) and a potent antimitotic agent, monomethyl auristatin E (MMAE), which inhibits cell division by blocking the polymerization of tubulin. Lifastuzumab vedotin has the potential for non-small cell lung cancer (NSCLC) and platinum-resistant ovarian cancer (PROC) research[1].
1401812-88-1
RG-7599; DNIB-0600A; NaPi2b-ADC
12352203
Antibody-Drug Conjugates (ADCs)
Antibody-drug Conjugate/ADC Related
Cancer
99.03
10 mM in DMSO
[Lifastuzumabvedotin]
[1]S Banerjee, et al. Anti-NaPi2b antibody-drug conjugate lifastuzumab vedotin (DNIB0600A) compared with pegylated liposomal doxorubicin in patients with platinum-resistant ovarian cancer in a randomized, open-label, phase II study. Ann Oncol. 2018 Apr 1;29 (4) :917-923.|[2]David E Gerber, et al. Phase Ia Study of Anti-NaPi2b Antibody-Drug Conjugate Lifastuzumab Vedotin DNIB0600A in Patients with Non-Small Cell Lung Cancer and Platinum-Resistant Ovarian Cancer. Clin Cancer Res. 2020 Jan 15;26 (2) :364-372.
Dry Ice
-80°C, protect from light
http://file.medchemexpress.com/batch_PDF/HY-P99705/Lifastuzumab-vedotin-SDS-MedChemExpress.pdf
ADC Related
Phase 2
Beschrijving
Lifastuzumab vedotin (RG-7599; DNIB0600A) is an antibody-drug conjugate (ADC) that comprises a humanized IgG1 anti-NaPi2b monoclonal antibody (MNIB2126A) and a
Specificaties
Recent bekeken producten
H&E Mount, Permanent Mountindg media for coverslipping H&E stains from water,
NB315
125 mL
SCD polyclonal antibody
GTR18043932-01
50 μL
(KO Validated) SUMO1 Polyclonal Antibody
E-AB-92410-01
60 µL
Salicylate hydroxylase, Microorganism
HY-E70520-01
1 KU
Purified Diphtheria Toxoid protein (cGMP/USP, vaccine grade, ~1500-2500 Lf/ml; Low endotoxin)
DTOX16-N-500
500 µg
BioCoupler® Glass Set (16 oz) x12
BCS1612
12 Each
BioCoupler® x 48
BC48
48 Each
BioTilt™ 25 (BT25)
BT25
25 Bundles
Recent gezochte producten
H&E Mount, Permanent Mountindg media for coverslipping H&E stains from water,
NB315-40
40 mL
Probe Mount, Permanent Mounting media for mounting and coverslipping of Special stains & Immunofluorescence and In-Situ Stains FROM WATER
NB316-30
30 mL
H&E Mount, Permanent Mountindg media for coverslipping H&E stains from water,
NB315
125 mL
Probe Mount, Permanent Mounting media for mounting and coverslipping of Special stains & Immunofluorescence & In-Situ Stains FROM WATER
NB316
60 mL
Holder for water tank for mounting
CHA4068
1 Each
Permount Mounting Medium
21750009-2
500 mL
Wall Mount for S1
TH9066-11
each
PROJECTION SCREEN, DELUXE Tripod Stand – foldable, metal stand, with four position vertical adjustment; for mounting of projection screens.
4022650/8
1 Each