LIFR Antilichaam

This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t (5;8) (p13; q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene.

3977

P42702

Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 500-700 of human LIFR (NP_002301.1) .

Unconjugated

Primary Antibodies

Cell Cycle, Chemokines & Cytokines, Immunology, Innate Immunity, Stem Cell

Affinity purification

Mouse skeletal muscle

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 190kDa

IgG

WB: 1:500 - 1:2000

LIFR

LIF receptor subunit alpha

Homo sapiens

CD118, LIF-R, SJS2, STWS, SWS, leukemia inhibitory factor receptor, CD118 antigen, LIF receptor, LIF receptor alpha, leukemia inhibitory factor receptor alpha

WB

Liquid