LILRB2 Antilichaam

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) . The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

10288

Q8N423

Human, Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 479-598 of human LILRB2 (NP_005865.3) .

Unconjugated

Primary Antibodies

Immunology

Affinity purification

THP-1

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 65kDa

IgG

WB: 1:500 - 1:2000

LILRB2

U-87MG

Leukocyte immunoglobulin like receptor B2

Homo sapiens

CD85D, ILT-4, ILT4, LIR-2, LIR2, MIR-1MIR1leukocyte immunoglobulin-like receptor subfamily B member 2, CD85 antigen-like family member D, Ig-like transcript 4, leucocyte Ig-like receptor B2, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2, monocyte/macrophage immunoglobulin-like receptor 1myeloid inhibitory receptor 10

WB

Liquid