LILRB3 Mouse Monoclonal Antibody [Kloon ID: LBI3G9]

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) . The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Carrier-free (BSA/glycerol-free) LILRB3 mouse monoclonal antibody, clone LBI3G9

CD85A; HL9; ILT-5; ILT5; LILRA6; LIR-3; LIR3; PIRB

Homo sapiens leukocyte immunoglobulin like receptor B3 (LILRB3), transcript variant 2, mRNA.

11025

O75022

Unconjugated

B cell receptor signaling pathway

B cell receptor signaling pathway

WB 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Transmembrane

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

LILRB3

https://www.ncbi.nlm.nih.gov/gene/?term=11025

https://www.uniprot.org/uniprot/O75022