LIMS2 Polyklonale Antilichaam, PE-vervoeging

Pinch is a focal adhesion protein that is a component of the ILK-PINCH complex. This complex is a major part of the growth factor and integrin signaling pathway. Pinch is involved in cell differentiation, proliferation and survival by acting as an effector of integrin and growth factor signaling. It is a cytoplasmic protein expressed in most tissues and consists of five LIM domains, a nuclear localization signal and a nuclear export signal. The PINCH-1/ILK complex is regulated by another member of the Pinch family, PINCH-2, which also forms a complex with ILK.

FLJ10044; ILK binding protein; LIM and senescent cell antigen like domains 2; LIM and senescent cell antigen-like-containing domain protein 2; LIM-like protein 2; LIMS2; LIMS2_HUMAN; Particularly interesting new Cys-His protein 2; PINCH 2; PINCH-2; PINCH2.

Nucleus

251-341/341

LIMS2

PE

KLH conjugated synthetic peptide derived from human LIMS2

IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

496,564nm/578nm

1µg/µl

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Human, Mouse, Rat, Dog, Cow, Pig, Horse, Chicken