LIN28 Antilichaam - N-terminaal gebied : FITC (ARP34477_P050-FITC)

Lin-28 homolog A (C. elegans)

CSDD1, LIN28, LIN-28, ZCCHC1, lin-28A

79727

Q9H9Z2

NP_078950

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Pig, Rabbit, Sheep, Yeast

The immunogen is a synthetic peptide directed towards the N terminal region of human LIN28

LIN28 acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. The association of LIN28 with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. IT binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. LIN28 is Essential for skeletal muscle differentiation program through the translational up-regulation of IGF2 expression.

HNRNPUL2; HNRNPA3; DHX36; SREK1; TRIM71; LARP4; TGS1; DHX57; GADD45GIP1; LTV1; NOA1; DDX50; KRI1; NOL6; METTL17; NOC3L; ZC3HAV1; PPAN; CCBL2; MEPCE; TSR1; NHP2; NOP10; STRBP; BRIX1; RBM28; PHAX; SRRT; LARP7; DDX41; HP1BP3; NOB1; PRPF19; ZBTB11; SND1; AATF

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

IHC, WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Goat: 91%; Guinea Pig: 86%; Human: 100%; Mouse: 90%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Yeast: 77%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

23kDa

Gregory, S.G., (2006) Nature 441 (7091), 315-321

Wet Ice

209

LIN28A

LIN28A

Rabbit

Protein lin-28 homolog A

NM_024674

GSVSNQQFAGGCAKAAEEAPEEAPEDAARAADEPQLLHGAGICKWFNVRM