LIN28B Antilichaam - C-terminaal gebied: Biotine (ARP50332_P050-Biotine)

Lin-28 homolog B

CSDD2

389421

Q6ZN17

NP_001004317

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep

The immunogen is a synthetic peptide directed towards the C-terminal region of Human LN28B

The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation.

LARP4; ZCCHC3; NIFK; NHP2; NOP10; PHAX; LARP7; TRUB2; PTCD1; RBM34; NCBP2; RALY; KRR1; EIF4A3; SNRPG; SNRPF; SNRPB2; SNRPA; PURB; PURA; NCBP1; FBL; ELAVL2; TRIM71; UBC; COPS5; USP36

Biotin

Polyclonal Antibody

WB

Affinity purified

0.5 mg/ml

Cow: 100%; Dog: 93%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 79%; Pig: 100%; Rabbit: 86%; Rat: 93%; Sheep: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

27kDa

Wet Ice

250

LIN28B

LIN28B

Rabbit

Protein lin-28 homolog B

GCTSPPFPQEARAEISERSGRSPQEASSTKSSIAPEEQSKKGPSVQKRKK