LIN28B (NM 001004317) Humaan Recombinant eiwit

The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012]

Purified recombinant protein of Human lin-28 homolog B (C. elegans) (LIN28B), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

CSDD2

389421

Q6ZN17

NM_001004317

6q16.3-q21

E. coli

N-GST and C-His

>50 ug/mL as determined by microplate BCA method

> 80% as determined by SDS-PAGE and Coomassie blue staining

Liquid

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.

54.9 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

LIN28B

Human

NP_001004317

https://www.ncbi.nlm.nih.gov/gene/389421

https://www.uniprot.org/uniprot/Q6ZN17

https://www.ncbi.nlm.nih.gov/nuccore/NM_001004317

https://www.ncbi.nlm.nih.gov/nuccore/NP_001004317