Lipohexine

Lipohexin is a peptide antibiotic. Lipohexin has anti-Gram-positive bacterial effect. Lipohexin had competitive inhibitory effect on human placental proline endopeptidase with an IC50 of 3.5 μM. Lipohexin inhibits the proline endopeptidase from the Flavobacterium meningoseptiu with an IC50 of 25 μM[1].

193751-58-5

12352005

Antibiotic; Bacterial; Prolyl Endopeptidase (PREP)

Anti-infection; Metabolic Enzyme/Protease

Infection

OC(CCNC(C(C)(C)NC(C(C)(C)NC(C(C)(C)NC(C(C)(C)NC([C@H]1N(CCC1)C(C(C)C(CCCCCCCCCCC)=O)=O)=O)=O)=O)=O)=O)=O

C39H68N6O9

764.99

[1]S Heinze, et al. Lipohexin, a new inhibitor of prolyl endopeptidase from Moeszia lindtneri (HKI-0054) and Paecilomyces sp. (HKI-0055; HKI-0096) . I. Screening, isolation and structure elucidation. J Antibiot (Tokyo) . 1997 May;50 (5) :379-83.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N5194/

Natural Products

No Development Reported