Lipopeptide CPE4

Lipopeptide CPE4 is a PEG-modified peptide E4 [ (EIAALEK) 4]. Lipopeptide CPE4 is capable of coiled-coil formation when attached to liposomes. Lipopeptide CPE4 triggers membrane fusion between liposomes and living cells with concomitant efficient cytosolic delivery of a variety of compounds such as fluorescent dyes Propidium Iodide (PI) and TO-PRO-3 iodide (HY-117070), and Doxorubicin (DOX) (HY-15142A). Lipopeptide CPE4 can be used for drug delivery research[1].

12352209

Liposome

Metabolic Enzyme/Protease

Others

CC(C)CCC[C@H]([C@@](CC[C@]1([C@@]2(CC=C(C3)[C@@]4(CC[C@@H]3NC(CCC(NCCOCCOCCOCCOCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CCCCN)=O)CCC(O)=O)=O)CC(C)C)=O)C)=O)C)=O)[C@H](CC)C)=O)CCC(O)=O)=O)CCCCN)=O)CCC(O)=O)=O)CC(C)C)=O)C)=O)C)=O)[C@H](CC)C)=O)CCC(O)=O)=O)CCCCN)=O)CCC(O)=O)=O)CC(C)C)=O)C)=O)C)=O)[C@H](CC)C)=O)CCC(O)=O)=O)CCCCN)=O)CCC(O)=O)=O)CC(C)C)=O)C)=O)C)=O)[C@H](CC)C)=O)CCC(O)=O)=O)=O)=O)C)[H])[H])([C@@](CC[C@@]24[H])1C)[H])C

C177H303N35O51

3737.50

[1]Yang J, et al. Drug Delivery via Cell Membrane Fusion Using Lipopeptide Modified Liposomes. ACS Cent Sci. 2016 Sep 28;2 (9) :621-630.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P11455/

Peptides

No Development Reported