Liraglutide-d8 (tetraTFA)

Liraglutide-d8 tetraTFA is deuterium labeled Liraglutide. Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used for the study of type 2 diabetes mellitus[1].

12352209

GLP Receptor; Isotope-Labeled Compounds

GPCR/G Protein; Others

Metabolism-protein/nucleotide metabolism

Metabolic Disease

0.982

O=C(CNC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@]([2H])(NC([C@H](NC([C@H](NC([C@H](NC([C@H](NC([C@H](NC(CNC([C@H](NC([C@H](NC([C@H](N)CC1=CNC=N1)=O)C)=O)CCC(O)=O)=O)=O)[C@H](C)O)=O)CC2=CC=CC=C2)=O)[C@H](C)O)=O)CO)=O)CC(O)=O)=O)C(C([2H])([2H])[2H])(C([2H])([2H])[2H])[2H])=O)CO)=O)CO)=O)CC3=CC=C(C=C3)O)=O)CC(C)C)=O)CCC(O)=O)=O)=O)CCC(N)=O)=O)C)=O)C)=O)CCCCNC(CC[C@H](NC(CCCCCCCCCCCCCCC)=O)C(O)=O)=O)=O)CCC(O)=O)=O)CC4=CC=CC=C4)=O)[C@H](CC)C)=O)C)=O)CC5=CNC6=C5C=CC=C6)=O)CC(C)C)=O)C(C)C)=O)CCCNC(N)=N)=O)=O)CCCNC(N)=N)=O)O.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

C180H261D8F12N43O59

4215.34

[1]Wang Y, et al. Transformation of oligomers of lipidated peptide induced by change in pH.Mol Pharm. 2015 Feb 2;12 (2) :411-9.

Room Temperature

-20°C, 3 years; 4°C, 2 years (Powder)

http://file.medchemexpress.com/batch_PDF/HY-P0014AS/

Isotope-Labeled Compounds

No Development Reported