Livin (BIRC7) Mouse Monoclonal Antibody [Kloon ID: LBI1B10]

The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide.

Carrier-free (BSA/glycerol-free) BIRC7 mouse monoclonal antibody, clone LBI1B10

KIAP; LIVIN; ML-IAP; MLIAP; RNF50

Homo sapiens baculoviral IAP repeat containing 7 (BIRC7), transcript variant 1, mRNA.

79444

Q96CA5

Unconjugated

WB 1:2000, IF 1:100, Flow 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

BIRC7

https://www.ncbi.nlm.nih.gov/gene/?term=79444

https://www.uniprot.org/uniprot/Q96CA5